The genetic diversity analysis in the donkey myostatin gene

作     者：LIU Dong-hua HAN Hao-yuan ZHANG Xin SUN Ting LAN Xian-yong CHEN Hong LEI Chu-zhao DANG Rui-hua 

作者机构：College of Animal Science and TechnologyNorthwest A&F University Institute of Hexi Ecology and Oasis AgricultureHexi University 

出 版 物：《Journal of Integrative Agriculture》 (农业科学学报（英文版）)

年 卷 期：2017年第16卷第3期

页      面：656-663页

核心收录：

学科分类：0710[理学-生物学] 0832[工学-食品科学与工程（可授工学、农学学位）] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 0905[农学-畜牧学] 0906[农学-兽医学] 09[农学] 0901[农学-作物学] 0703[理学-化学] 0902[农学-园艺学] 0713[理学-生态学] 

基　　金：supported by the National Natural Science Foundation of China (31072001  31272399  81270439) 

主　　题：Chinese donkey myostatin gene SNP genetic diversity 

摘      要：Myostatin（MSTN）gene negatively controls skeletal muscle development and growth,variations of which play an important role in the regulation of skeletal muscle growth in ***,study on genetic polymorphism of MSTN gene in donkey is *** this study,we screened the single nucleotide polymorphsims（SNPs）of MSTN gene in 13 Chinese donkey *** novel SNPs（g.229T〉C,g.872A〉G,g.2014G〉A,and g.2395C〉G）were detected and genotyped by sequencing and polymerase chain reaction-restriction fragment length polymorphism（PCR-RFLP）*** haplotypes（H1–H6）were analyzed,which indicated abundant haplotype diversities in Chinese *** haplotype H1 was the most dominant and ancient in all *** donkey displayed the highest haplotype *** Neighbour-Joining（NJ）tree of MSTN gene among different species was *** clustering result of nine species was consistent with the fact of species *** results will provide a reliable theoretical basis for the preservation,exploration and utilization of Chinese donkey genetic resources.