BMI and BMI Changes to All-cause Mortality among the Elderly in Beijing： a 20-year Cohort Study

作     者：WANG Yun Feng TANG Zhe GUO Jin TAO Li Xin LIU Long LI Hai Bin LI Di Tian GUO Xiu Hua YANG Xing Hua 

作者机构：School of Public Health Capital Medical University Beijing 100069 China Beijing Municipal Key Laboratory of Clinical Epidemiology Beijing 100069 China School of Basic Medical Sciences Peking University Health Science Center Beijing 100191 China School of Basic Medical Sciences Peking University Health Science Center Beijing100191 China 

出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)

年 卷 期：2017年第30卷第2期

页      面：79-87页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：supported by the Beijing Natural Science Foundation(7131002) the Key Projects in the National Science&Technology Pillar Program in the Twelfth Five-year Plan Period of China(2011BAI08B01) the Beijing Municipal Natural Science Foundation(Serial Number:7122016) 

主　　题：Body mass index All-cause mortality The elderly Beijing 

摘      要：Objective To explore the association between body mass index （BMI） and all-cause mortality among the elderly in Beijing. Methods This analysis was based on the Beijing multidimensional longitudinal study of aging （BLSA）, which included 2,090 subjects over 55 years old and was followed-up from 1992 to 2012. BMI-mortality curves were drawn to find the optimal BMI range with the lowest mortality. Cox proportional hazard models were used to obtain the hazard ratios （HRs） for BMI and BMI changes in the overall population and in specific stratified populations. Results During follow-up, 2,264 deaths were recorded; BMI-mortality curve was U-shaped, with the lowest mortality at a BMI of approximately 25 kg/m2. After adjusting for gender, age, smoking, drinking and some pre-existing diseases, HRs for underweight, overweight and obesity compared with normal weight were 2.372 （95% C/： 2.254-2.632）, 0.767 （95% CI： 0.666-0.884） and 0.872 （95% CI： 0.830-1.246）, respectively. HR for BMI drop was 3.245 （95% CI： 0.824-22.772） in the underweight group and 1.892 （95% C/： 0.830-1.246） in the normal weight group, HR for BMI rise was 1.795 （95% CI： 1.243-2.591） in normal weight group and 2.962 （95% CI： 2.202-3.203） in the overweight group. Conclusion Keeping BMI in an overweight status and stable is related to a reduced mortality