State-of-art modelling of inflammatory astrocyte-synapse interactions in injury and amyotrophic lateral sclerosis
State-of-art modelling of inflammatory astrocyte-synapse interactions in injury and amyotrophic lateral sclerosis作者机构:John van Geest Centre for Brain RepairDepartment of Clinical NeurosciencesUniversity of CambridgeCambridgeUnited Kingdom Department of NeurologyAddenbrooke's HospitalCambridge University Hospitals NHS TrustCambridgeUnited Kingdom
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2017年第12卷第1期
页 面:75-76页
核心收录:
学科分类:0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100204[医学-神经病学] 10[医学]
基 金:MRC [MR/P008658/1] Funding Source: UKRI Medical Research Council [MR/P008658/1] Funding Source: Medline
主 题:astrocyte amyotrophic neuronal synaptic modulating insight viability glutamate inflammation NMDAR
摘 要:Different outcomes of astrocyte inflammatory signalling in injury and neurodegeneration:It is emerging that astrocytes have a significant impact on the neuronal network by modulating synaptic connections and neuronal viability in both normal and pathological states.