Evolving strategies for liver fibrosis staging: Non-invasive assessment

作     者：cristina Stasi Stefano Milani 

作者机构：Department of Experimental and Clinical MedicineUniversity of Florence Department of BiomedicalExperimental and Clinical SciencesUniversity of Florence 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2017年第23卷第2期

页      面：191-196页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

主　　题：Elastography 非侵略的方法 长期的肝疾病 僵硬 非侵略的浆液标记 

摘      要：Transient elastography and the acoustic radiation force impulse techniques may play a pivotal role in the study of liver fibrosis. Some studies have shown that elastography can detect both the progression and regression of fibrosis. Similarly, research results have been analysed and direct and indirect serum markers of hepatic fibrosis have shown high diagnostic accuracy for advanced fibrosis/cirrhosis. The prognosis of different stages of cirrhosis is well established and various staging systems have been proposed, largely based on clinical data. However, it is still unknown if either noninvasive markers of liver fibrosis or elastography may contribute to a more accurate staging of liver cirrhosis, in terms of prognosis and fibrosis regression after effective therapy. In fact, not enough studies have shown both the fibrosis regression in different cirrhosis stages and the point beyond which the prognosis does not change- even in the event of fibrosis regression. Therefore, future studies are needed to validate noninvasive methods in predicting the different phases of liver cirrhosis.