Large-scale genome-wide scans do not support petaloid toenail as a Mendelian trait

作     者：Manfei Zhang Sijie Wu Juan Zhang Yajun Yang Jingze Tan Haijuan Guan Yu Liu Kun Tang Jean Krutmann Shuhua Xu Li Jin Yaqun Guan Hui Li Sijia Wang 

作者机构：Ministry of Education Key Laboratory of Contemporary AnthropologyCollaborative Innovation Center for Genetics and DevelopmentSchool of Life SciencesFudan UniversityShanghai 200438China Chinese Academy of Sciences Key Laboratory of Computational BiologyCAS-MPG Partner Institute for Computational BiologyShanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 200031China University of Chinese Academy of SciencesBeijing 100049China Fudan-Taizhou Institute of Health SciencesTaizhou 225300China IUF-Leibniz Research Institute for Environmental MedicineDusseldorf 40225Germany School of Life Science and TechnologyShanghai Tech UniversityShanghai 200031China Department of Biochemistry and Molecular BiologyPreclinical Medicine CollegeXinjiang Medical UniversityUrumqi 830011China 

出 版 物：《Journal of Genetics and Genomics》 (遗传学报（英文版）)

年 卷 期：2016年第43卷第12期

页      面：702-704页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071007[理学-遗传学] 

基　　金：supported by the National Natural Science Foundation of China(Nos.31322030,91331108 to S.W 31222030 to H.L 30890034,31271338 to L.J 91331204,31171218 to S.X 31260263 to Y.G.) the National Basic Research Program(No.2015FY111700 to L.J.) the Ministry of Education(No.113022A toH.L.) the Chinese Academy of Sciences(No.XDB13040100 to S.X.) the National Program for Top-notch Young Innovative Talents of The“Wanren Jihua”Project to S.X the National Thousand Young Talents Award to S.W the Shanghai Shuguang Project(No.14SG05)to H.L the Max Planck-CAS Paul Gerson Unna Independent Research Group Leadership Award to S.W the open projects from the State Key Laboratory of Genetic Engineering,Fudan University to S.W 

主　　题：meta mode than 

摘      要：Petaloid toenail, or accessory nail of the fifth toe, is a physical trait characterized by the presence of an additional tiny toenail on the small toe. Since it can occasionally cause disfigurement and tenderness while wearing tight shoes or walking, standard surgical matricectomy is often carried out to repair the petaloid toenail （Chi and Wang, 2004）. Chinese legends recorded petaloid toenails as a trait unique to Han Chinese （Gao, 2010）, but population- based studies are largely absent.