Stem cells and neurodegenerative diseases

作     者：HOU LingLing & HONG Tao Institute of Biological Science and Technology, Beijing Jiaotong University, Beijing 100044, China 

作者机构：Institute of Biological Science and Technology Beijing Jiaotong University Beijing 100044 Chin 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2008年第51卷第4期

页      面：287-294页

核心收录：

学科分类：0808[工学-电气工程] 0710[理学-生物学] 0820[工学-石油与天然气工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1002[医学-临床医学] 0817[工学-化学工程与技术] 0807[工学-动力工程及工程热物理] 0827[工学-核科学与技术] 0703[理学-化学] 100204[医学-神经病学] 0701[理学-数学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 10[医学] 

基　　金：the Talented Person Foundation of Beijing Jiaotong University (Grand No. 2004RC048) the Great Science and Technology Foundation of Beijing Jiaotong University (Grand No. 2004SZ010) 

主　　题：stem cells neurodegenerative diseases therapy 

摘      要：Neurodegenerative diseases are characterized by the neurodegenerative changes or apoptosis of neurons involved in networks, which are important to specific physiological functions. With the de-velopment of old-aging society, the incidence of neurodegenerative diseases is on the increase. How-ever, it is difficult to diagnose for most of neurodegenerative diseases. At present, there are too few effective therapies. Advances in stem cell biology have raised the hope and possibility for the therapy of neurodegenerative diseases. Recently, stem cells have been widely attempted to treat neurodegen-erative diseases of animal model. Here we review the progress and prospects of various stem cells, including embryonic stem cells, mesenchymal stem cell and neural stem cells and so on, for the treatments of neurodegenerative diseases, such as Parkinson’s disease, Alzheimer’s disease, Hunt-ington’s disease and Amyotrophic lateral sclerosis/Lou Gehrig’s disease.