Altered Resting-State Signals in Patients with Acute Stroke In or Under the Thalamus

作     者：Lijun Chen Chuanfu Li Jian Zhai Anqin Wang Qin Song Ying Liu Ru Ma Long Han Yamikani Ndasaukas Xiaoming Li Hai Li Xiaochu Zhang 无

作者机构：Chinese Academy of Sciences Key Laboratory of Brain Function and Disease and School of Life SciencesUniversity of Science and Technology of ChinaHefei 230026 China Department of Medical Iconography Anhui University of Chinese Medicine Hefei 230031 China Department of Medical Iconography Yijishan Hospital of Wannan Medical College Wuhu 241001 China Department of Medical Iconography Provincial Hospital Affiliated to Anhui Medical University Hefei 230001 China School of Humanities and Social Science University of Science and Technology of China Hefei 230026 China Center of Medical Physics and Technology Hefei Science Center Chinese Academy of Sciences Hefei 230031 China Center for Biomedical Engineering University of Scienceand Technology of China Hefei 230027 China 

出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)

年 卷 期：2016年第32卷第6期

页      面：585-590页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：supported by grants from the National Natural Science Foundation of China(31230032,31171083, and 31471071) Fundamental Research Funds for the Central Universities of China(WK2070000033) the Natural Science Foundation of Anhui Province,China(1208085MH179) Hefei Science Center,CAS "User with Potential"(2015HSC-UP017) 

主　　题：ReHo - Stroke Thalamus - Resting-state 

摘      要：Abstract Previous studies have suggested that cortical functional reorganization is associated with motor recovery after stroke and that normal afferent sensory information is very important in that process. In this study, we selected patients who had a stroke in or under the thalamus, with potentially impaired afferent sensory information and analyzed the differences between these patients and healthy controls at three levels： brain regions, the functional con- nectivity between brain areas, and the whole-brain func- tional network. Compared with healthy controls, regionalhomogeneities in the left middle temporal gyrus decreased and functional connectivity between the left middle tem- poral gyrus and the stroke area increased in the patients. However, there was no significant change in the whole- brain functional network. By focusing on stroke located in or under the thalamus, our study contributes to wider inquiries into understanding and treating stroke.