May headache be the first sign of mutation in the MTHFR gene?

作     者：Suber Dikici Ayhan Saritas Fahri Halit Besir Gokhan Celbek Guven Arslan 

作者机构：Department of NeurologySchool of MedicineDuzce UniversityDuzceTurkey Department of Emergency MedicineSchool of MedicineDuzce UniversityDuzceTurkey Department of RadiologySchool of MedicineDuzce UniversityDuzceTurkey Department of Internal MedicineSchool of MedicineDuzce UniversityDuzceTurkey 

出 版 物：《World Journal of Emergency Medicine》 (世界急诊医学杂志（英文）)

年 卷 期：2013年第4卷第1期

页      面：69-72页

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：Cerebral venous thrombosis Headache Methylenetetrahydrofolate reductase gene mutation 

摘      要：BACKGROUND:Cerebral venous thrombosis(CVT) is a rare disease and it has different *** or acquired prothrombotic state plays a key role in the development of ***:A 28-year-old man who presented to our emergency department with persistent headache and accompanied by complaints of nausea and vomiting over a *** examination revealed bilateral *** computed tomography showed a hyperdense area on the posterior part of the occipital *** magnetic resonance imaging and magnetic resonance venography revealed thrombosis of *** mutations were found for methylenetetrahydrofolate reductase(MTHFR).MTHFR CG677 T gene mutation and blood tests showed elevated homocysteine levels on the etiological *** was no other etiology for ***:Headache and other complaints were improved after treatment of heparin,warfarin,and vitamin *** recurrence of symptoms was observed upon outpatient ***:Since CVT is an important cause of headache,we recommend etiology screening for patients who present with CVT for MTHFR gene mutations and family counseling should be provided.