Crystal structure of HLA-B＊5801, a protective HLA allele for HIV-1 infection

作     者：Xiaolong Li Pedro A. Lamothe Robert Ng Shutong Xu Maikun Teng Bruce D. Walker Jia-huai wang 

作者机构：School of Life Sciences University of Science and Technology of China Hefei 230027 China Department of Medical Oncology and Cancer Biology Dana- Farber Cancer Institute Harvard Medical School Boston MA 02215 USA Ragon Institute of Massachusetts General Hospital Massachusetts Institute of Technology Harvard University Boston MA 02139 USA Howard Hughes Medical Institute Chevy Chase MD 20815 USA Department of Pediatrics and Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School Boston MA 02115 USA Present address: Biomarin Pharmaceutical 790 Lincoln Ave San Rafael CA 94901 USA 

出 版 物：《Protein & Cell》 (蛋白质与细胞（英文版）)

年 卷 期：2016年第7卷第10期

页      面：761-765页

核心收录：

学科分类：090603[农学-临床兽医学] 0710[理学-生物学] 07[理学] 08[工学] 09[农学] 0906[农学-兽医学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

基　　金：Harvard University Center for AIDS Research CFAR to Bruce Walker supported by a Ragon Innovation Award 

摘      要：Conquering the AIDS epidemic remains one of the most challenging global health issues. Despite impressive advances in combination antiretroviral therapy （cART） to treat HIV, and substantial progress in the development of prevention interventions, a protective vaccine has remained elusive.