Chemo-type of essential oil of Ocimum basilicum *** DR Congo and relative in vitro antioxidant potential to the polarity of crude extracts

作     者：Dorothee Dinangayi Tshilanda Philippe Bila Babady Damase Nguwo Vele Onyamboko Christian Muamba Tshilolo Tshiongo Damien Sha-Tshibey Tshibangu Koto-te-Nyiwa Ngbolua Philippe Vuka Tsalu Pius Tshimankinda Mpiana 

作者机构：Department of ChemistryFaculty of ScienceUniversity of Kinshasa Bila Nutraceuticals Company Department of BiologyFaculty of ScienceUniversity of Kinshasa 

出 版 物：《Asian Pacific Journal of Tropical Biomedicine》 (亚太热带生物医学杂志（英文版）)

年 卷 期：2016年第6卷第12期

页      面：1022-1028页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Supported by Longjin Company Sarl for the Research Grant(DD Tshilanda LCS/1020-SU-160710) Organization for the Prohibition of Chemical Weapons for the Training Grant(Ref.S/1295/2015) 

主　　题：Ocimum basilicum L. Essential oil Polar and non-polar crude extracts In vitro antioxidant potential GC-MS analysis 

摘      要：Objective:To carry out a phyto-chemical characterization of essential oil from Ocimum basilicum L.(***) harvested in DR Congo and to assess the antioxidant potential of crude extracts with respect to the polarity for comparison ***:The phyto-chemical characterization of essential oil produced by hydrodistillation was performed by coupled gas chromatography-mass spectrometer analysis and the antioxidant potential evaluation by in vitro 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity ***:A previously weighed amount of fresh leaves of *** produced 0.65%of essential oil that led to the identification of a set of 84.44%out of 99.98%as major compounds( 1.5%).The chemo-type of this essential oil was linalool-methyl *** components of oil were characterized by oxygenated aromatic hydrocarbons(46.00%) and oxygenated monoterpenes(26.75%).With respect to the amount of components,methyl chavicol also known as estragole(35.72%) constituted the very large quantity afterward linalool(21.25%) and then epi-α-cadinol(8.02%),α-bergamotene(6.56%),eugenol(4.60%),1,8-cineole(4.04%),germacrene D(2.06%),thymol(1.64%),and(E)-citral(1.55%),*** oil exhibited antioxidant potential and IC_(50) =(1.180 ± 0.015) mg/***-polar crude extracts yields were low compared to the one of polar *** methanol and ethyl acetate had considerably manifested antioxidant potential with IC_(50) values equal to(0.025 ± 0.013) mg/mL and(0.085 ± 0.012) mg/mL,*** concerns to IC50 values,essential oil was less active than methanol and ethyl acetate *** methanol crude extract exhibited the highest ***-polar extracts showed insignificant radical scavenging ability that did not allow assessing IC50 *** results highlighted the occurrence of antioxidant potential compounds in polar ***:Essential oil and crude extracts of *** growing in DR Congo can be advocated as nat