Relationship between Job Stress and Hypo-high-density Lipoproteinemia of Chinese Workers in Shanghai： The Rosai Karoshi Study

作     者：Tomohiko Muratsubaki Tomomi Hattori Jue Li Shin Fukudo Masanori Munakata Muratsubaki Tomohiko;Hattori Tomomi;Li Jue;Fukudo Shin;Munakata Masanori

作者机构：Department of Behavioural MedicineTohoku University Graduate School of MedicineSendai 980-8575Japan Research Centre for Lifestyle-Related DiseaseTohoku Rosai HospitalSendai 981-8563Japan HeartLung and Blood Vessel Research CentreTongji University School of MedicineShanghai 200092China Division of HypertensionTohoku Rosai HospitalSendai 981-8563Japan 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2016年第129卷第20期

页      面：2409-2415页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by the grant from the Japan Labor  Health  and Welfare Organization 

主　　题：Chinese Workers Hypo-high-density Lipoproteinemia Job Stress 

摘      要：Background：Karoshi,or death due to overwork,has now become a serious social problem in *** of cardiovascular risks by stress might initiate *** studies have examined the relationship between job stress and obesity,hypertension,and type 2 diabetes mellitus,but less evidence exists for dyslipidemia like hypo-high-density lipoproteinemia （hypo-HDL）.The aim of this study was to investigate the relationship between job stress and hypo-HDL of Chinese workers in ***：We studied 2219 Chinese workers in Shanghai,who participated in the Japan-China cooperative study for the prevention of karoshi.A questionnaire was administered to examine the lifestyle characteristics,job category,weekly working hours,and job *** demand and job control were quantified using the National Institute for Occupational Safety and Health *** job strain measure was defined by the combination of low job control and high ***-HDL was defined as plasma high-density lipoprotein cholesterol concentration of〈1.04 mmol/L （40 mg/dl）.Multivariate logistic regression analysis was performed for hypo-HDL as a dependent ***：Modified job strain was not related to hypo-HDL either in men or *** men,multivariate adjusted odds ratio （OR） for having hypo-HDL was significantly higher in the lowest job control tertile compared with the highest job control tertile （OR =1.39,95% confidence interval [CI] 1.03-1.87,P =0.034）.In the same model,a similar trend was observed for women,but it did not reach a statistically significant level （OR =1.51,95% CI,0.88-2.56,P =0.132）.Conclusion：A low level of job control but not modified job strain was significantly related to higher prevalence ofhypo-HDL of Chinese workers in Shanghai.