A regioselective synthesis of pentacyclic compounds containing coumarin,pyrrole,indene without catalysts under microwave irradiation

作     者：Zhi-Wei Chen Jun-Bo Hou Zhao-Ran Dai Xiao-Feng Yang 

作者机构：Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of EducationCollege of Pharmaceutical SciencesZhejiang University of Technology 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2016年第27卷第10期

页      面：1622-1625页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 10[医学] 

基　　金：the National Natural Science Foundation of China(No.21276237)for financial support 

主　　题：4-Aminocoumarin Catalyst-free Ninhydrin Regioselective Annulation 

摘      要：A concise and efficient approach was developed for the synthesis of pentacyclic compounds containing coumarin, pyrrole, indene in a regioselective manner in good yields via the reactions of N-substituted 4- aminocoumarin compounds and ninhydrin using microwave irradiation. No catalysts are required in our protocol.