Parthenolide:a novel pharmacological approach to promote nerve regeneration
Parthenolide:a novel pharmacological approach to promote nerve regeneration作者机构：Division of Experimental Neurology Department of NeurologyHeinrich-Heine-University
出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)
年 卷 期：2016年第11卷第10期
页 面：1566-1567页
核心收录：
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
基 金：supported by the German Research Foundation(DFG)
摘 要：Traumatic axonal lesions disrupt the connections between neurons and their targets, leading to loss of motoric and sensory functions. Although lesioned peripheral nerves can principally regenerate, the rate of recovery depends on the mode and severity of the respective injury （Grinsell and Keating, 2014）. While injuries close to the innervation site have good chances of recovery, long distance regeneration is particularly problematic due to relatively slow axonal growth rates, which even under favorable conditions do not normally exceed 1-2 mm per day （Sunderland, 1947）.
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