Modulatory effect of catecholamines and corticosterone on proliferative activity of thymic and splenic lymphocytes

作     者：Liu Shuzheng,Han Zhenbo.Liu Weihong,Ju Guizhi,Qi Jin(MPH Radiobiology Research Unit,PRC) 

出 版 物：《吉林大学学报(医学版)》 (Journal of Jilin University(Medicine Edition))

年 卷 期：1993年第3期

页      面：219-223页

核心收录：

基　　金：Supported by a grant from NNSF  PRC 

主　　题：catecholamines/PD corticosterone/PD lymphocyte proliferation/DE thymus/CY Spleen/CY 

摘      要：Epinephrine (E) in concentrations of 10-1000 nmol/L,norepinephrine (NE) in concentrations of 100-300 nmol/L and corticosterone (CS) in concentrations of 1 - 50 pmol/L potentiated the reactivity of thymic and splenic lymphocytes to Con A as well as the spontaneous proliferation of thymocytes in normal mice. It is first reported in the present paper that catecholamines (CA’s) and CS showed a synergistic effect in potentiating the reactivity of thymic and splenic lymphocytes to Con A when they were added to culture in concentrations ineffective each of its own. The implications of these results were discussed.