HEMOGLOBIN WUMING (all [A9] Lsy→Gln), A NEW HEMOGLOBIN VARIANT FOUND IN CHINA
HEMOGLOBIN WUMING (all [A9] Lsy→Gln), A NEW HEMOGLOBIN VARIANT FOUND IN CHINA作者机构:Laboratory of Medical Genegics Shanghai Children's Hospital Guangxi Medical College Nanning Institute of Haemotology Chinese Academy of Medical Sciences Tianjin Department of Biochemistry
出 版 物:《Chinese Science Bulletin》 (科学通报(英文版))
年 卷 期:1982年第27卷第10期
页 面:1135-页
学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题:hemoglobin cellulose appearance bands A9 Gln Lsy all chains acetate
摘 要:During the survey of hemogiobinopathies, a fast moving hemoglobin was found in one Chinese male of Zhuang nationality in Wuming County of tire Zhuang Autonomous Region of Guangxi. Same electrophoretic bands were found in seven persons in his family. The propositus was healthy in appearance, having no clinical symptom at all and being normal also in haemotology. The abnormal hemoglobin in his hemolysate was evaluated by cellulose acetate membrane electrophoresis and found to be 19.4%. Isolation of the globin chains was performed by CM-cellulose chromatography in 8M urea and one fast chain (a^x chain)