EFFECT OF HIGH TIDAL VOLUME VENTILATION AND LIPOPOLYSACCHARIDE ON MITOGEN-ACTIVATED PROTEIN KINASE IN RAT LUNG TISSUE
Effect of high tidal volume ventilation and lipopolysaccharide on mitogen-activated protein kinase in rat lung tissue作者机构：Department of Critical Care Medicine Zhong-da Hospital and School of Clinical Medicine Southeast University Nanjing 210009 China
出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)
年 卷 期：2006年第119卷第1期
页 面：53-56页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金：THIS WORK WAS SUPPORTED BY GRANTS FROM GREAT TOPIC FOUNDATION OF HEALTH BUREAU JIANGSU PROVINCE CHINA (NO. H200102) AND SARS SPECIAL FOUNDATION OF SOUTHEAST UNIVERSITY NANJING JIANGSU PROVINCE CHINA (NO. 9290006003)
主 题：mechanical ventilation high tidal volume lipopolysaccharide mitogen-activated protein kinase inflammatory mediator
摘 要：Mechanical ventilation, a crucial therapy to acute respiratory distress syndrome （ARDS）,could exacerbate lung injury, and even result in ventilator-induced lung injury （VILI） if misused in some condition1. Over-activating inflammatory cells and expanding inflammatory responses, which are induced by infection, are fundamental reasons for ARDS. Among them,
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