THE CRYSTAL STRUCTURE OF N-(TBUTOXYCARBONYL)-L-METHIONYL GLYCINE ETHYL ESTER

作     者：严友为 董贻诚 唐有祺 YAN YOUWEI DONG YICHENG AND TANG YOUQI (Institute of Biophysics, Academia Sinica, Beijing )

作者机构：Institute of Biophysics Academia Sinica Beijing 

出 版 物：《Science in China,Ser.B》 (中国科学B辑(英文版))

年 卷 期：1985年第28卷第8期

页      面：835-843页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

主　　题：卜工 L-METHIONYL GLYCINE ETHYL ESTER TBUTOXYCARBONYL THE CRYSTAL STRUCTURE OF N BOC 

摘      要：The crystal structure of N-（t-butoxycarbonyl）-L-methionyl-glycine ethyl ester has been determined. The crystal data are: P21, α=14.504（6）, b=5.015（2）, c=12.762（6）, β=93.63（3）°, Z=2. The final R is 0.066 for 1495 reflections. The torsion angles of methionyl side chain are X1=-177.7°. X2=178.6°, X3=-71.7°. The plan of the side chain is approximately vertical to the plan of the peptide. The peptide main chains are packed in a parallel β-sheet structure, the main chain torsion angles（φ,ψ） of the methionyl residue being （-118.9°,115.4°）. This compound, BOC-L-Met-Gly-OEt, is very similar to certain derivatives used in the peptide transport studies which were carried out by Naider et al.