E-ROSETTE FORMATION WITH SRBC AND CHANGES IN cAMP LEVEL OF HOG LYMPHOCYTES——A STUDY OF CERTAIN AFFECTING FACTORS

作     者：管远志 石镜 谢少文 GUAN YUANZHI;SHI JING;XIE SHAOWEN Immunology Department, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing

作者机构：Immunology Department Institute of Basic Medical Sciences Chinese Academy of Medical Sciences Beijing 

出 版 物：《Science in China,Ser.B》 (中国科学B辑(英文版))

年 卷 期：1982年第25卷第1期

页      面：62-67页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：SRBC cAMP E-ROSETTE FORMATION WITH SRBC AND CHANGES IN cAMP LEVEL OF HOG LYMPHOCYTES A STUDY OF CERTAIN AFFECTING FACTORS 

摘      要：A further study of cAMP change in porcine lymphocytes after E-rosette formation ispresented in the present report using peripheral blood lymphocytes of pig mixed with differentconcentrations of SRBC membrane as well as SRBC treated with different enzymes formodification of the rosette formation. It has been found that cAMP enhancement in lymphocytefollows the increase in the concentration of SRBC membrane used, and that a similar relationappeared between modification of cAMP and enzyme-treated SRBC in the rosette formation. Ithas also been found that after rosetting wtth SRBC, cAMP level of lymphocytes began to risewithin 1 min, reached its peak at 10 min and then returned to control leveI in about 8 hr.