Risk factors of choledocholithiasis formation after liver transplantation

作     者：Zhi-Yong Yu Min Zhang Yun-Sheng Qin Xiao-Ping Zhou Ming-Yue Cai Song-Feng Yu Qing-Hong Ke Shu-Sen Zheng 

作者机构：Division of Hepatobiliary and Pancreatic Surgery Key Laboratory of Combined Multi-organ Transplantation Ministry of Public Health and Key Laboratory of Organ Transplantation Zhejiang Province First Affiliated Hospital Zhejiang University School of Medicine 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2013年第12卷第2期

页      面：215-217页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：supported by grants from the Team Program of Science and Technology Bureau of Zhejiang Province(2009R50038) the Health Bureau of Zhejiang Province Foundation (B1652) 

主　　题：liver transplantation endoscopic retrograde cholangiopancreatography choledocholithiasis biliary tract diseases common bile duct stone gallstones 

摘      要：Systematic study of risk factors for biliary stone post-liver transplantation is rarely performed. To investigate the risk factor of choledocholithiasis formation after liver transplantation, we c onducted a case-control study. Fourteen patients were selected into a study group. The stones of the bile duct of the patients were confirmed and treated successfully by endoscopic retrograde cholangiopancreatography. For univariate analysis, we selected carefully some potential risk factors such as cold ischemia time, warm ischemia time, and biliary stricture. The results revealed that cold ischemia time and biliary stenosis were significant predictors. But multivariate analysis revealed that only biliary stenosis was a significant risk factor. In conclusion, biliary stenosis is a risk factor of bile duct stones formation after liver transplantation. Endoscopic retrograde cholangiopancreatography is effective and safe in the diagnosis or treatment of bile duct stones after liver transplantation.