Study on the bitter principles from Tacca plants——Structures of taccalonolides A and B

作     者：CHEN Zhong-Liang* WANG Bao-De, Shanghai Institute of Materia Medica, Academia Sinica, ShanghaiCHEN Min-Quin, Department of Chemistry, Fudan University, Shanghai 

作者机构：Shanghai Institute of Materia Medica Academia Sinica Shanghai Department of Chemistry Fudan University Shanghai 

出 版 物：《Chinese Journal of Chemistry》 (中国化学(英文版))

年 卷 期：1988年第6卷第3期

页      面：251-256页

学科分类：07[理学] 0703[理学-化学] 

主　　题：Structures of taccalonolides A and B Study on the bitter principles from Tacca plants 

摘      要：We isolated four steroidal bitter principles from the rhizome of Tacca plantaginea *** structures of taccalonolides A (1) and B (2) were elucidated by spectral and chemical methods, asa new type of pentacyclic steroidal γ-lactone. Taccalonolide A shows cytotoxic activity against P-388leukemia in cell culture and antimalarial activity to Plasmodium berghai.