Intra-operative peritoneal lavage for colorectal cancer
Intra-operative peritoneal lavage for colorectal cancer作者机构：Departement of General and Surgical OncologyHospices Civils de Lyon69495 Pierre BéniteFrance EMR 3738Université Lyon 1F-69364 LyonFrance
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2014年第20卷第8期
页 面：1935-1939页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Peritoneal carcinomatosis Colorectal cancer Free intraperitoneal cells Immunocytochemistry
摘 要：Free cancer cells can be detected in peritoneal fluid at the time of colorectal surgery. Peritoneal lavage in colorectal surgery for cancer is not used in routine, and the prognostic significance of intraperitoneal free cancer cells (IPCC) remains unclear. Data concerning the technique of peritoneal lavage to detect IPCC and its timing regarding colorectal resection are scarce. However, positive IPCC might be the first step of peritoneal spread in colorectal cancers, which could lead to early specific treatments. Because of the important heterogeneity of IPCC determination in reported studies, no treatment have been proposed to patients with positive IPCC. Herein, we provide an overview of IPCC detection and its impact on recurrence and survival, and we suggest further multi-institutional studies to evaluate new treatment strategies.
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