Antidotal effects of curcumin against neurotoxic agents:An updated review

作     者：Tahereh Farkhondeh Saeed Samarghandian Fariborz Samini 

作者机构：Department of ImmunogeneticsBuAli Research InstituteMashhad University of Medical Sciences Department of Basic Medical SciencesNeyshabur University of Medical Sciences Department of NeurosurgeryFaculty of MedicineMashhad University of Medical Sciences 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2016年第9卷第10期

页      面：924-931页

核心收录：

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主　　题：Curcumin Neurotoxic agents Antioxidant Antidote 

摘      要：Curcumin(CUR), the main phenolic composition in turmeric, shows preventive effects in various diseases. CUR is commonly found in the Curcuma species and historically applied in herbal medicine. Numerous studies have indicated that CUR possesses protective effects against toxic agents in the various animal tissues including the brain. This study found that CUR may be effective in nervous system problems induced by neurotoxic agents. However, due to the lack of information on human, more investigations are needed to determine the efficacy of CUR as an antidote matter. The current study aimed to critically review the recent literature data from 2014 to 2016 that regarding the therapeutic aspects of CUR versus neurotoxic agents-induced brain damage and its involved mechanisms.