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Possible divergence of serum-and glucocorticoid-inducible kinase function in ischemic brain injury

Possible divergence of serum-and glucocorticoid-inducible kinase function in ischemic brain injury

作     者:Koichi Inoue 

作者机构:Department of Integrative AnatomyNagoya City University Graduate School of Medical Sciences 

出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))

年 卷 期:2016年第11卷第9期

页      面:1396-1397页

核心收录:

学科分类:1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主  题:SGK Possible divergence of serum-and glucocorticoid-inducible kinase function in ischemic brain injury 

摘      要:As recent medical progress decreases the incidence of certain diseases, ischemic brain injury remains one of the major dis- eases that threaten human lives, especially in western countries. Ischemic brain injury occurs as a result of lack of oxygen and nutrients due to obstruction of blood flow in the brain, and often leads to neurological disorders such as cerebral palsy, depression, and ultimately, death. Around 800,000 Americans suffer a new or recurrent stroke, and more than 130,000 people die annually in the United States (Goldstein et al., 2011). Despite much effort in searching for an effective treatment, at most a few reagents are approved for therapeutic medication in many countries.

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