Synthesis and Structure of R- (+)-CamphorDerived N-Propionyl Sultam

作     者：HUANG Jin-xia PAN Yi-Jun and XU Zhang-huang(Deparinient of Chemistry , Hubei University , Wuhan , 430062 )CHEN Liao-rong and LUO Bao-sheng(Analysis and Testing Center , Wuhan University , 430072 ) 

作者机构：HUBEI UNIVDEPT CHEMWUHAN 430062PEOPLES R CHINA WUHAN UNIVCTR ANAL & TESTINGWUHAN 430072PEOPLES R CHINA 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：1995年第11卷第1期

页      面：32-38页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 

主　　题：N-Propionyl sultam Potential chiral Crystal structure 

摘      要：potential chiral auxilliary, (+)-camphor derived N-propionyl sultam, wassynthesized from (+ )-camphor-10-sulphonyl chloride in four steps with enan-tiomerical purity. The molecular and crystal structures of the title compound weredetermined by single crystal diffraction analysis. The crystal belongts to monoclin-ic , space group P2_1 with cell dimentions a= 1. 0502(4) , b= 0. 7252(1 ) , c= 0. 9363(2) nm, β= 108. 3(5) , V = 0. 677 nm￣3, F(000) = 292 and Z= 2. The structuralcharacteristics with respect to the potential utility for the stereoselective alkylationat a-carbon of the N-propionyl group are discussed and explained based on ￣1H-, ￣(13)C-NMR. MS and X-ray analysis.