Synthesis and Biological Activity of Novel 2,3-Dihydro-2-phenylsulfonylhydrazono-3-(2′,3′,4′,6′-tetra-O-acetyl-β-D-glucopyranosyl)thiazoles
Synthesis and Biological Activity of Novel 2,3-Dihydro-2-phenylsulfonylhydrazono-3-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)thiazoles作者机构:Elemento-Organic Chemistry Institute State Key Laboratory of Elemento-Organic Chemistry National Pesticide Engineering Research Center Nankai University Tianjin 300071 P. R. China
出 版 物:《Chemical Research in Chinese Universities》 (高等学校化学研究(英文版))
年 卷 期:2009年第25卷第1期
页 面:52-55页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 100701[医学-药物化学] 10[医学]
基 金:Supported by the National Basic Research Program of China(No.2003CB114406) the Science and Technology Innova-tion Foundation of Nankai University, China
主 题:Synthesis 2,3-Dihydrothiazole Biological activity
摘 要:A series of novel 2,3-dihydro-2-phenylsulfonylhydrazono-3-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)thiazoles were designed and synthesized via the reaction of thiosemicarbazide with chloroaldehyde. Their chemical structures were characterized by ^1H and ^13C NMR spectroscopy and elemental analysis. The bioassay results indicate that some of these compounds exhibit moderate fungicidal and herbicidal activities.