Anti Toxoplasma antibodies prevalence and associated risk factors among HIV patients

作     者：Dechassa Tegegne Mukarim Abdurahaman Tadesse Mosissa Moti Yohannes 

作者机构：Department of Microbiology and Veterinary Public Health Jimma University Department of Natural Resource Management Jimma University 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2016年第9卷第5期

页      面：446-451页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：funded by Jimma University College of Agriculture and Veterinary Medicine(NO.6223) 

主　　题：Toxoplasma gondii HIV LAT Seroprevalence 

摘      要：Objective: To assess the seroprevalence and associated risk factors of toxoplasmosis among HIV patients in Agaro Town Health Center of Jimma zone. Methods: Convenient sampling was used to collect blood samples from 135 patients attending anti retroviral therapy from February to March 2015. Serum samples were tested for anti-Toxoplasma gondii(T. gondii) antibody by using latex agglutination test. Structured questionnaire was used to collect data on socio-demographic and risk factors associated with toxoplasmosis. Results: Overall seroprevalence of toxoplasmosis was 80.7%(109/135, CI: 74.04-87.36). In multivariate analysis significant association was observed between anti T. gondii seropositivity and raw meat consumption(OR: 3.514, CI: 1.167 10.581, P=0.025), knowledge about toxoplasmosis(OR: 5.225, CI: 1.382, P=0.015) and sex(OR: 4.023, CI: 1.382-19.762, P=0.015). Conclusions: Immuno compromised patients showed high rate of seropositivity and thus, it is highly advisable to introduce routine anti-T. gondii antibodies serological screening test prior to ART commencement.