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Role of Raman spectroscopy and surface enhanced Raman spectroscopy in colorectal cancer

Role of Raman spectroscopy and surface enhanced Raman spectroscopy in colorectal cancer

作     者:Cerys A Jenkins Paul D Lewis Peter R Dunstan Dean A Harris 

作者机构:Swansea University Medical SchoolSwansea University Department of PhysicsCollege of ScienceCenter for NanohealthSwansea University Department of Colorectal SurgerySingleton Hospital 

出 版 物:《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志(英文版)(电子版))

年 卷 期:2016年第8卷第5期

页      面:427-438页

核心收录:

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基  金:Supported by Cancer Research Wales No.248767 

主  题:Detection Colorectal cancer Spectroscopy Raman Surface enhanced Raman Spectroscopy 

摘      要:Colorectal cancer(CRC) is the fourth most commoncancer in the United Kingdom and is the second largest cause of cancer related death in the United Kingdom after lung *** in the United Kingdom there is not a diagnostic test that has sufficient differentiation between patients with cancer and those without cancer so the current referral system relies on symptomatic presentation in a primary care *** spectroscopy and surface enhanced Raman spectroscopy(SERS) are forms of vibrational spectroscopy that offer a nondestructive method to gain molecular information about biological *** techniques offer a wide range of applications from in vivo or in vitro diagnostics using endoscopic probes,to the use of micro-spectrometers for analysis of *** techniques have the potential to detect molecular changes prior to any morphological changes occurring in the tissue and therefore could offer many possibilities to aid the detection of *** purpose of this review is to look at the current state of diagnostic technology in the United *** development of Raman spectroscopy and SERS in clinical applications relation for CRC will then be ***,future areas of research of Raman/SERS as a clinical tool for the diagnosis of CRC are also discussed.

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