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“Magic” of our gastric cancer results on perioperative chemotherapy

“Magic” of our gastric cancer results on perioperative chemotherapy

作     者:Carlos León-Espinoza Fernando López-Mozos Roberto Marti-Obiol Marina Garces-Albir Joaquin Ortega-Serrano 

作者机构:Department of Digestive and General SurgeryHospital Clínico Universitario de Valencia 

出 版 物:《World Journal of Gastrointestinal Pathophysiology》 (世界胃肠病理生理学杂志(英文版)(电子版))

年 卷 期:2016年第7卷第3期

页      面:283-287页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Stomach neoplasms Perioperative period Chemotherapy 

摘      要:AIM: To determine reproducibility of perioperative chemotherapy for gastric cancer(GC) on our settings by identifying patient s overall survival and comparing them to larger ***: Retrospective analysis of our series,where we present our eleven-year s experience on GC managed according to perioperative approach of three preoperative chemotherapy cycles followed by surgery and finally three postoperative chemotherapy *** scheme used was Xelox(Oxaliplatin and Capecitabine).Epidemiologic parameters as well as surgical variables were analysed,presented,and compared to other series with similar *** was estimated by Kaplan Meier/log rank method and also compared to these ***: Mean age was 65 years *** survival in our series was 37.7%,similar to other groups using perioperative *** was 4% and morbidity 30%,which are also similar to those *** curves were compared to larger studies,finding similarities on *** survival analysis between chemotherapy responders and non-responders didn t reach statically significant ***: Perioperative chemotherapic scheme can be reproduced on our setting with good results and without increasing morbidity or mortality.

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