Treating chronic hepatitis B virus:Chinese physicians' awareness of the 2010 guidelines

作     者：Lai Wei Ji-Dong Jia Xin-Hua Weng Xiao-Guang Dou Jia-Ji Jiang Hong Tang Qin Ning Qing-Qing Dai Run-Qin Li Jie Liu 

作者机构：Department of HepatologyPeking University People’s Hospital Department of HepatologyBeijing Friendship HospitalCapital Medical University Department of Infectious DiseaseShanghai Huashan Hospital Department of Infectious DiseaseShengjing Hospital of China Medical University Department of Hepatologythe First Affiliate Hospital of Fujian Medical University Department of Infectious DiseaseWest China HospitalSichuan University Department of Infectious DiseaseAffiliated Tongji Hospital of Tongji Medical College Bristol-Myers Squibb 

出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)

年 卷 期：2016年第8卷第18期

页      面：762-769页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：Supported by Bristol-Myers Squibb 

主　　题：Chronic hepatitis B Practice guidelines Awareness China Physicians 

摘      要：AIM: To investigate Chinese physicians awareness of the 2010 guidelines on the treatment of chronic hepatitis B virus(HBV) ***: This was a quantitative survey that investigated the characteristics and practices of physicians who were treating patients with hepatitis B, the profile of their patients and physician practices regarding the diagnosis and treatment of HBV at the time of the survey. Participants were randomly selected from available databases of Chinese physicians and requested to complete either an online or paper-based survey. Data from the survey responses were analysed. For data validation and interpretation, qualitative in-depth interviews were conducted with 39 of the ***: Five-hundred completed surveys, from 663 physicians were available for analysis. A mean of 175 chronic hepatitis B(CHB) patients was seen by each physician every month, of whom 85(49%) were treated in line with therapeutic indications stated in the 2010 guidelines. A total of 444(89%) physicians often( 60% of the time) adhered to the guidelines. Most physicians used antiviral medications as recommended. For patients with compensated and decompensated cirrhosis, 342(68%) and 336(67%) of physicians, respectively, often followed the recommendation to use potent nucleos(t)ide analogues with a high genetic barrier to resistance, using the appropriate treatment more than 60% of the time. Physicians from infectious disease or liver disease departments were better informed than those from gastrointestinal or other ***: The majority of Chinese physicians often adhere to Chinese 2010 CHB guidelines and are well-informed about the use of antiviral medications for hepatitis B.