The More Efficacious Acupoints of Zusanli and Sanyinjiao Than That of Non-acupoints on Bone Mass in Osteopenic Ovariectomized Rats

作     者：张文平 KANEHARA Masayuki 张艳军 于志锋 张国霞 杨幼新 孙玉敏 张建梅 ISHIDA Torao 

作者机构：Institute of Traditional Chinese Medicine Suzuka University of Medical Science Tianjin College of Traditional Chinese Medicine 

出 版 物：《Chinese Journal of Integrated Traditional and Western Medicine》 (中国中西医结合杂志（英文版）)

年 卷 期：2005年第11卷第3期

页      面：209-216页

学科分类：1005[医学-中医学] 100512[医学-针灸推拿学] 10[医学] 

主　　题：acupuncture osteopenia ovariectomy bone mineral density histomorphometry 

摘      要：Objective： To clarify whether the acupoints of Zusanli （ST36） and Sanyinjiao （SP6） have specific actions other than non-acupoints to bone. Methods： Forty Sprague-Dawley female rats were divided into five groups： Sham operated （sham） group; Ovariectomized （OVX, model） group; non-acupuncture group; OVX, needling on Zusanli and Sanyinjiao （Acp-A） group; OVX, needling on the reverse sides of Zusanli and Sanyinjiao （Acp-B） group; OVX, periostineal stimulation on the same height as points of Zusanli and Sanyinjiao （Acp-C） group. The experiment was continued for 23 weeks and then all animals were sacrificied. Results： OVX had a significantly higher body weight and lower bone mineral density （BMD） on the lumbar vertebrae, total femora and tibiae than sham rats, however, Acp-A showed a higher BMD compared with the other OVX groups. On the other hand, bone weights, bone strength and bone morphometry such as trabecular volume, trabecular separation, labeled width and bone formation rate also showed the same improvements in Acp-A as compared to the other OVX rats. Conclusion： The stimulation on Zusanli and Sanyinjiao specifically prevented the development of osteopenic rats compared with non-acupoints.