A Xanthomonas oryzae pv. oryzae effector, Xop R, associates with receptor-like cytoplasmic kinases and suppresses PAMP-triggered stomatal closure

作     者：Shuangfeng Wang Jianhang Sun Fenggui Fan Zhaoyun Tan Yanmin Zou Dongping Lu 

作者机构：State Key Laboratory of Plant Genomics Center for Agricultural Research Resources Institute of Genetics and Developmental Biology Chinese Academy of Sciences Shijiazhuang Hebei 050021 China University of Chinese Academy of Sciences Beijing 100049 China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2016年第59卷第9期

页      面：897-905页

核心收录：

学科分类：09[农学] 0904[农学-植物保护] 090401[农学-植物病理学] 

基　　金：supported by the National Natural Science Foundation of China(31322009) the National Basic Research Program of China(2015CB910200) the State Key Laboratory of Plant Genomics of China(SKLPG2011B0301,SKLPG2011A0301) 

主　　题：Xanthomonas effector XopR BIK1 immunity 

摘      要：Receptor-like kinases(RLKs) play important roles in plant immunity signaling; thus, many are hijacked by pathogen effectors to promote successful pathogenesis. Xanthomonas oryzae pv. oryzae(Xoo) is the causal agent of rice leaf blight disease. The strain PXO99 A has 18 non-TAL(transcription activation-like) effectors; however, their mechanisms of action and host target proteins remain largely unknown. Although the effector XopR from the Xoo strain MAFF311018 was shown to suppress PAMP-triggered immune responses in Arabidopsis, its target has not yet been identified. Here, we show that PXO99 A XopR interacts with BIK1 at the plasma membrane. BIK1 is a receptor-like cytoplasmic kinase(RLCK) belonging to the RLK family of proteins and mediates PAMP-triggered stomatal immunity. In turn, BIK1 phosphorylates XopR. Furthermore, XopR suppresses PAMP-triggered stomatal closure in transgenic Arabidopsis expressing XopR. In addition, XopR is able to associate with RLCKs other than BIK1. These results suggest that XopR likely suppresses plant immunity by targeting BIK1 and other RLCKs.