衣原体性结膜炎与视网膜中央静脉阻塞

作     者：Stewart M.W Liesegang T.J Schwam B.L 桑延智 

作者机构：Department of Ophthalmology 4500 San Pablo Rd. Jacksonville FL 32082 United States.Dr 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2005年第1卷第12期

页      面：19-19页

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：衣原体性结膜炎 衣原体肺炎 血清学阳性 干预性 沙眼衣原体 血管性疾病 多西环素 局部炎症 滤泡 敏感反应 

摘      要：PURPOSE: To report a case of coexistent Chlamydia conjunctivitis and central retinal vein occlusion (CRVO) in which both problems improved significantly after oral doxycyline. DESIGN: Interventional case report. METHODS: A healthy 39- year-old man presented with follicular and papillary conjunctivitis, unresponsive to topical antibiotic therapy, and a CRVO. The patient had serum IgG titers of 1:256 to both Chlamydia pneumonia and Chlamydia trachomatous. RESULTS: Treatmentwith oral doxycyline (100 mg orally twice daily for 2 weeks) resulted in complete resolution of the conjunctivitis and rapid improvement of the CRVO. CONCLUSIONS: Because of its ability to cause chronic vascular endothelial infection and localized inflammation, Chlamydia has been implicated in the development of arterial vascular disease. The positive Chlamydia serology, conjunctivitis, CRVO, and excellent response to doxycycline in this patient suggest that Chlamydiamay have contributed to his vascular occlusion. Further studies investigating a possible association between Chlamydia and CRVO may be indicated.