Cell-specific mineralocorticoid receptors:future therapeutic targets for stroke?

作     者：Quynh N.Dinh Grant R.Drummond Christopher G.Sobey Sophocles Chrissobolis 无

作者机构：Vascular Biology & Immunopharmacology GroupCardiovascular Disease Program and Department of PharmacologyBiomedicine Discovery InstituteMonash University Department of Pharmaceutical and Biomedical SciencesRaabe College of PharmacyOhio Northern University 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2016年第11卷第8期

页      面：1230-1231页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 10[医学] 

基　　金：supported by a postdoctoral fellowship from the National Health and Medical Research Council (NHMRC) of Australia the Foundation for High Blood Pressure Research Australia (to SC) grants from the NHMRC and the National Heart Foundation of Australia 

主　　题：aldosterone homeostasis electrolyte outside inflammation deletion neurological protective infarct remodeling 

摘      要：The mineralocorticoid receptor（MR）,well known to be expressed in renal epithelial cells where it is important in fluid and electrolyte homeostasis,has aldosterone as one of its main *** research in the last 10–15 years indicates that MRs are also expressed outside of the kidney,including in the brain,vasculature and heart,where they contribute to the pathophysiology of disease（Dinh et al.,2012;]aisser and Farman, 2016）.