Effects of Exogenous Carbon Monoxide Releasing Molecules on the Development of Zebrafish Embryos and Larvae

作     者：SONG Jing E SI Jing ZHOU Rong LIU Hua Peng WANG Zhen Guo GAN Lu GUI Fang LIU Bin ZHANG Hong 

作者机构：School/Hospital of Stomatology Lanzhou University Lanzhou 730000 Gansu China Department of Medical Physics Institute of Modern Physics Chinese Academy of Sciences Lanzhou 730000 Gansu China Key Laboratory of Heavy Ion Radiation Biology and Medicine Chinese Academy of Sciences Lanzhou 730000 Gansu China Key Laboratory of Heavy Ion Radiation Medicine of Gansu Province Lanzhou 730000 Gansu China Gansu Medicinal College Pingliang 744000 Gansu China Lanzhou veolia Water(Group) Co. Ltd Lanzhou 730000 Gansu China 

出 版 物：《Biomedical and Environmental Sciences》 (生物医学与环境科学（英文版）)

年 卷 期：2016年第29卷第6期

页      面：453-456页

核心收录：

学科分类：100405[医学-卫生毒理学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 10[医学] 

基　　金：supported by National Basic Research Program of China(2010CB834202) the National Natural Science Foundation of China(11305226,11175222) the Scientific Technology Research Projects of Lanzhou City(2015-3-75) the Western Talent Program of Chinese Academy of Sciences(Y460030XB0) 

主　　题：CO Effects of Exogenous Carbon Monoxide Releasing Molecules on the Development of Zebrafish Embryos and Larvae 

摘      要：The use of exogenous carbon monoxide releasing molecules（CORMs）provides promise for clinical application;however,the hazard potential of CORMs in vivo remains poorly *** developmental toxicity of CORM-3 was investigated by exposure to concentrations ranging from 6.25 to400μmol/L during 4-144 h post *** endpoints of mortality,spontaneous movement,heart rate,hatching rate,malformation,body length,and larval behavior were measured.