Effect of fasting on blood parameters of SD rats

作     者：Rabigul ISLAM Yultuz MAMAT Anargul MAHMUT Mahsut KADIR YAN Ming 

作者机构：Center for Evaluation of Drug safety of Xinjiang Inistitute of Traditional Uyghur Medicine Prescription of Xinjiang Traditional Uyghur Medicine 

出 版 物：《中国药理学与毒理学杂志》 (Chinese Journal of Pharmacology and Toxicology)

年 卷 期：2013年第3期

页      面：558-558页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

主　　题：fasting rats,SPF blood parameters 

摘      要：OBJECTIVE To explore the effects of fasting on blood biochemistry,blood cells,blood electrolyte and and plasma prothrombin time of SPF SD *** Fourty SPF SD rats were adaptive breeding for 90 d Serum alanine transaminase(ALT),aspartate transaminase(AST),alkaline phosphatase(ALP),creatine kinase(CK),total protein(TP),Albumin,total cholesterol(CHO),triglycerides(TG),glucose(GLU),creatinine(Crea),total bilirubin(TBIL),urea nitrogen(BUN),red blood cell count(RBC) and its classification,white blood cell count(WBC) and its classification,platelet count(PLT),electrolyte ion concentration(K +,Na +,Cl-),prothrombin time(PT) were detected on the 91 *** On the fasting group(♂) : TG,CHOlevels were decreased and TBIL,TP,ALB,WBC and Na + levels were increased in serum(P 0.01);on the fasting group(♀) : TG,MCHC levels were decreased and TBIL,ALB and Na + levels were increased in serum(P 0.01).CONCLUSION Fasting can influenceon the blood parameters of SPF SD rats.