ADVANCE IN ACUPOINT SPECIFICITY STUDY BASED ON NEUROIMAGING TECHNIQUES

作     者：Fanrong Liang 

作者机构：Chengdu University of Traditional Chinese Medicine 

出 版 物：《Journal of Integrative Medicine》 (结合医学学报(英文))

年 卷 期：2014年第3期

页      面：237-237页

学科分类：1005[医学-中医学] 100512[医学-针灸推拿学] 10[医学] 

主　　题：MIG FD ADVANCE IN ACUPOINT SPECIFICITY STUDY BASED ON NEUROIMAGING TECHNIQUES 

摘      要：Objective: To reveal the central mechanism of acupoint ***: The research was conducted on patients with functional dyspepsia(FD) and migraine(MIG) undergoing acupuncture by applying functional magnetic resonance imaging and positron emission computed ***: FD patients:(1) Significant difference in cerebral glucometabolism between FD patients and healthy subjects(HS) was found and some brain areas were negatively correlated with NDI scoring.(2) Different acupoint selection methods had different impacts on brain functions of FD *** patients:(1) Compared with HS, decreased gray matter density of right insula, cerebral glucose metabolism and resting functional connectivity in MIG were detected.(2) Compared with non-acupoint group and non-involved-meridian group, Shaoyang meridian group showed relative specificity on cerebral glucose metabolism after acupuncture.(3) After acupuncture on the acupoints along Shaoyang meridian, the functional connectivity network of right insula in MIG became similar with that in healthy subjects.(4) The change of functional connectivity in right insula-DLPFC was negatively correlated with comprehensive score improvements in Shaoyang meridian group.(5) With fMRI data prior acupuncture, 2 weeks and 4 weeks after acupuncture, compared with non-acupoints, the persistent or alternative rise was witnessed in the pain-related brain regions of MIG in the group of specific acupoints of Shaoyang meridian, meanwhile the functional connectivity network of anterior cingulated cortex was in the process of dynamic ***: Compared with healthy subjects, the brain functions of the patients with FD or MIG were significantly different; acupuncture on the involved meridian has a relative specificity on central response characteristics.