T-bet in the spot light: roles in distinct T-cell fate determination
T-bet in the spot light: roles in distinct T-cell fate determination作者机构:Department of Surgery University of IllinoisCollege of Medicine Peoria IL USA
出 版 物:《Cellular & Molecular Immunology》 (中国免疫学杂志(英文版))
年 卷 期:2013年第10卷第4期
页 面:289-291页
核心收录:
学科分类:090603[农学-临床兽医学] 08[工学] 080203[工学-机械设计及理论] 09[农学] 0906[农学-兽医学] 0802[工学-机械工程]
主 题:Innate lymphoid cells T-bet T helper cell subsets
摘 要:The transcription factor T-bet was originally described to be important for the differentiation of the CD4+ Thl subset. More recent investigations implicate T-bet in the lineage commitment of a variety of innate immune cells also. The T-bet appears to have a dual role in the immune system.