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T-bet in the spot light: roles in distinct T-cell fate determination

T-bet in the spot light: roles in distinct T-cell fate determination

作     者:Sundararajan Jayaraman 

作者机构:Department of Surgery University of IllinoisCollege of Medicine Peoria IL USA 

出 版 物:《Cellular & Molecular Immunology》 (中国免疫学杂志(英文版))

年 卷 期:2013年第10卷第4期

页      面:289-291页

核心收录:

学科分类:090603[农学-临床兽医学] 08[工学] 080203[工学-机械设计及理论] 09[农学] 0906[农学-兽医学] 0802[工学-机械工程] 

主  题:Innate lymphoid cells T-bet T helper cell subsets 

摘      要:The transcription factor T-bet was originally described to be important for the differentiation of the CD4+ Thl subset. More recent investigations implicate T-bet in the lineage commitment of a variety of innate immune cells also. The T-bet appears to have a dual role in the immune system.

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