Personalized prostate cancer care: from screening totreatment
Personalized prostate cancer care: from screening totreatment作者机构:Program for Personalized Cancer Care NorthShore University HealthSystem 1001 University Place Evanston IL 60201 USA.
出 版 物:《Asian Journal of Andrology》 (亚洲男性学杂志(英文版))
年 卷 期:2016年第18卷第4期
页 面:505-508页
核心收录:
学科分类:0710[理学-生物学] 12[管理学] 120203[管理学-旅游管理] 1202[管理学-工商管理] 1002[医学-临床医学] 07[理学] 071007[理学-遗传学]
主 题:genetic risk score prostate cancer pyramid model single nucleotide polymorphisms
摘 要:Unprecedented progress has been made in genomic personalized medicine in the last several years, allowing for more individualized healthcare assessments and recommendations than ever before. However, most of this progress in prostate cancer (PCa) care has focused on developing and selecting therapies for late-stage disease. To address this issue of limited focus, we propose a model for incorporating genomic-based personalized medicine into all levels of PCa care, from prevention and screening to diagnosis, and ultimately to the treatment of both early-stage and late-stage cancers. We have termed this strategy the "Pyramid Model" of personalized cancer care. In this perspective paper, our objective is to demonstrate the potential application of the Pyramid Model to PCa care. This proactive and comprehensive personalized cancer care approach has the potential to achieve three important medical goals: reducing mortality, improving quality of life and decreasing both individual and societal healthcare costs.