复发性脱髓鞘性脊髓炎与丙肝病毒感染有关
Recurrent demyelinating myelitis associated with hepatitis C viral infection出 版 物：《世界核心医学期刊文摘（神经病学分册）》 (Digest of the World Core Medical Journals:Clinical Neurology)
年 卷 期：2005年第1卷第2期
页 面：50-51页
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
主 题：脱髓鞘性 丙肝病毒感染 自身免疫病 肝组织活检 血管炎 鉴别诊断 免疫机制
摘 要：We report a 46 year old man who developed recurrent myelitis associated wit h hepatitis C viral (HCV) infection. Spinal cord biopsy showed acute demyelinati on without evidence of vasculitis. Antibodies to HCV were present in the CSF;HCV RNA was not detected in the CSF. Neither HCV antigens nor RNA were detected in the spinal cord biopsy, whereas they were found in the liver biopsy. Evaluation for other infectious or autoimmune causes was unrevealing. These observations su ggest that recurrent myelitis in this patient is etiologically related to HCV in fection, possibly via an immune mediated mechanism. This is the first report of pathologically proven myelitis associated with HCV infection and we suggest tha t HCV be considered in the differential diagnosis of the transverse myelitis syn drome.
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