Peri-infarct reorganization at the centrum semiovale and corona radiata A diffusion tensor tractography and functional MRI study

作     者：Ji Heon Hong Sung Ho Jang 

作者机构：Department of Physical Therapy Yeungnam College of Science & Technology Namgu Daegu 705-717 Republic of Korea Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Daegu 705-717 Republic of Korea 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2011年第6卷第11期

页      面：826-829页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100204[医学-神经病学] 10[医学] 

基　　金：the National Research Foundation of Korea Grant Funded by the Korean Government  No. KRF-2008-314-E00173 

主　　题：diffusion tensor imaging functional MRI centrum semiovale corticospinal tract perilesional reorganization motor recovery neural regeneration 

摘      要：Peri-infarct reorganization has been reported in stroke patients with a lesion at the cerebral cortex, corona radiata, or pons, separately. However, there have been no reports describing the patients with peri-infarct reorganization at multiple levels. The present study reported a patient with a middle cerebral artery infarct who showed complete paralysis of the right extremities at stroke onset. Results showed that at 3 years after stroke onset, patient＇s motor function of the affected hand appeared to have been recovered by the motor tract, which reorganized into the anterior areas of the infarcted centrum semiovale and corona radiata, as demonstrated by diffusion tensor tractography study analyzed using functional MRI activation results. This result indicates that the human brain can show extensive brain plasticity and that saving the adjacent area or penumbra around the infarct even though the lesion from multiple levels is important for functional recovery after stroke.