Improvements in quality of life in septuagenarians versus octogenarians undergoing trans-catheter aortic valve replacement

作     者：Nuray Kahraman Ay Yasin Ay Osman Sonmez Mehmet Akif Vatankulu Omer Goktekin 

作者机构：Department of Cardiology Bezmialem Vakif University Fatih Istanbul Turkey Department of Cardiovascular Surgery Bezmialem Vakif University Fatih Istanbul Turkey 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2016年第13卷第5期

页      面：439-443页

核心收录：

学科分类：02[经济学] 0201[经济学-理论经济学] 1002[医学-临床医学] 020105[经济学-世界经济] 08[工学] 0837[工学-安全科学与工程] 

主　　题：生活质量 主动脉 患者 置换 导管 早期死亡率 老年人 队列研究 

摘      要：BACKGROUND:Very elderly patients represent a distinct patient group in clinical setting in terms of a decision for trans-catheter aortic valve replacement (TAVR) when one considers the potential improvement in the quality of life (QoL) on one hand and the benefit to risk ratio on the other. This study aimed to compare functional and QoL outcomes of TAVR between octogenarians and septuagenarians.;METHODS:This prospective cohort study included 136 elderly patients (70 to 89 years of age), who underwent transfemoral TAVR due to degenerative aortic stenosis. Patients were allocated into one of the following age groups: septuagenarians (n = 67) and octogenarians (n = 69). Preoperative and early postoperative clinical parameters were recorded. In addition, QoL of the patients was evaluated using SF-36 questionnaire preoperatively and six month postoperatively.;RESULTS:Groups were similar in terms of early postoperative mortality and morbidity parameters. The mean New York Heart Association (NYHA) class improved after TAVR in both groups. In addition, all SF-36 norm-based scale and SF-36 summary scale scores improved significantly in both groups during the postoperative period. Postoperatively, physical functioning, general health and physical component summary scores were significantly better in the septuagenarian group (P = 0.02, 0.01, 0.03, respectively).;CONCLUSIONS:Although the improvement in the QoL in terms of physical health was more marked in septuagenarians than in octogenarians, substantial benefits on the QoL and particularly on mental health seem to justify re-consideration of TAVR indications in the very elderly.