Comparison of the effects of first and second generation silicone hydrogel contact lens wear on tear film osmolarity

作     者：Guzin Iskeleli Yunus Karakoc Ahmet Ozkok Ceyhun Arici Omer Ozcan Osman Ipcioglu 

作者机构：Department of OphthalmologyCerrahpasa School of MedicineIstanbul University Department of BiophysicsInonu University Department of BiochemistryGata Haydarpasa Training Hospital 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2013年第6卷第5期

页      面：666-670页

核心收录：

学科分类：1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

主　　题：dry eye silicone hydrogel contact lens contact lens related dry eye tear film osmolarity 

摘      要：AIM:To compare the effects of first and second generation silicone hydrogel(SiH) contact lens wear on tear film ***:The healthy subjects who have never used contact lenses before were enrolled in the *** film osmolarity values of 16 eyes(group 1) who wore first generation SiH contact lenses were compared with those of 18 eyes(group 2) who wore second generation SiH contact lenses after three months ***:Beforecontactlenswear,tearfilmosmolarity of groups 1 and 2 were 305.02±49.08 milliosmole(mOsm) and 284.66±30.18mOsm,*** three months of contact lens wear,osmolarity values were found 317.74±60.23mOsm in group 1 and 298.40±37.77mOsm in group *** osmolarity values for both groups of SiH contact lens wear after three months periods were slightly higher than before the contact lens wear,the difference was not statistically significant. CONCLUSION:Contact lens wear may cause evaporation from the tear film and can increase tear film osmolarity leading to symptoms of dry eye *** the current study,there is a tendency to increase tear film osmolarity for both groups of SiH contact lens wear,but the difference is not statistically significant.