Equilibrium radionuclide angiocardiography:Its usefulness in current practice and potential future applications

作     者：Deepanjan Mitra Sandip Basu 

作者机构：Department of Nuclear Medicine and PET CT North City Diagnostic Centre Radiation Medicine Centre Bhabha Atomic Research Centre TMH Annexe Parel Mumbai 400012 India 

出 版 物：《World Journal of Radiology》 (世界放射学杂志（英文版）（电子版）)

年 卷 期：2012年第4卷第10期

页      面：421-430页

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1006[医学-中西医结合] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100106[医学-放射医学] 10[医学] 100602[医学-中西医结合临床] 

主　　题：Equilibrium radionuclide Angiocardiography Multigated acquisition Left ventricular ejection fraction Diastolic parameters Dyssynchrony 

摘      要：The routine and potential future applications of equilibrium radionuclide angiocardiography/multigated acquisition (MUGA) in clinical decision making are explored in this review. The non-invasive nature of the test, less operator dependence, lower radiation dose and ease of performing, even in ill patients, are important considerations in clinical cardiology practice. Two important routine uses of this modality in day-to-day clinical practice include the following: serial assessment of left ventricular ejection fraction (LVEF) in patients receiving cardiotoxic chemotherapy, and determination of accurate LVEF in patients with intractable heart failure. Other potential utilities of MUGA that could be translated into clinical practice include determination of regional LVEF, obtaining information about both right and left ventricle in suitable patients as a part of first pass angiocardiography, identification of diastolic dysfunction in patients with heart failure with preserved LVEF, and demonstration of dyssynchrony prior to cardiac resynchronisation, specifically by MUGA single photon emission *** last two indications are particularly important and evolving at this point.