自然周期体外受精结合未成熟卵母细胞体外成熟培养是治疗不孕的潜在方法
Natural-cycle in vitro fertilization combined with in vitro maturation of immature oocytes is a potential approach in infertility treatment出 版 物：《世界核心医学期刊文摘（妇产科学分册）》 (Core Journal in Obstetrics/Gynecology)
年 卷 期：2005年第1卷第5期
页 面：34-35页
学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学]
主 题：体外成熟培养 体外受精 未成熟卵母细胞 移植胚胎 取卵 显微注射 小卵泡 月经周期 吸出 生殖中心
摘 要：To describe pregnancies and live births that resulted from IVF of mature oocyt es retrieved from dominant follicles in a natural cycle combined with in vitro m aturation (IVM) of immature oocytes retrieved from small follicles. Case reports . McGill Reproductive Center, Royal Victoria Hospital, McGill University. Three women with normal ovaries or polycystic ovaries who underwent infertility treatm ent. Administration of SC hCG (10,000 IU) 36 hours before oocyte retrieval in a nat ural cycle. After aspiration of all follicles, mature oocytes were inseminated i mmediately; immature oocytes were matured in vitro, inseminated by intracytoplas mic sperm injection (ICSI), and then the embryos transferred. Pregnancy and live birth. Three pregnancies (two live births and one ongoing at time of writing) w ere achieved after the combination of natural-cycle IVF with IVM after transfer of the resulting embryos. Naturalcycle IVF combined with IVM might be a new app roach to IVF treatment for women with various causes of infertility.
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