Microwave-assisted reactions:Three-component process for the synthesis of 2-amino-2-chromenes under microwave heating

作     者：Ramadan A.Mekheimer Kamal U.Sadek 

作者机构：Chemistry DepartmentFaculty of ScienceEl-Minia University61519 El-MiniaEgypt 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2009年第20卷第3期

页      面：271-274页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the AvH Foundation for donation of milestone microwave labstation which is of great help in finishing this work 

主　　题：2-Amino-2-chromenes Microwave irradiation 

摘      要：2-Amino-2-chromenes are class of heterocycles that posses considerable interest as pigments, cosmetics, potential agrochemicals and being the main constituents of many natural products. Although, they are generally prepared either under conventional heating, benign reagents or very recently, a three component condensation in polyethylene glycol-water in the presence of nanosized magnesium oxide, most of these methods require prolonged reaction time, reagents in stoichiometric amounts and generate moderate yields of products. Microwave technique performs a better yield in a short reaction time （85-94%; 5-8 min）. Also, three-component one step reaction is of great interest for cost savings from the point of raw materials, energy and time, A combination between both techniques will be attractive for researchers in that field.