Beneficial effects of fenugreek glycoside supplementation in male subjects during resistance training: A randomized controlled pilot study

作     者：Sachin Wankhede Vishwaraman Mohan Prasad Thakurdesai 

作者机构：Department of Microbiology Smt.Kashibai Navale Medical College Department of Scientific AffairsIndus Biotech Private Limited 

出 版 物：《Journal of Sport and Health Science》 (运动与健康科学（英文）)

年 卷 期：2016年第5卷第2期

页      面：176-182页

核心收录：

学科分类：0403[教育学-体育学] 040302[教育学-运动人体科学(可授教育学、理学、医学学位)] 04[教育学] 

基　　金：supported by the Indus Biotech Private Ltd. Pune with no role in the collection analysis and interpretation of data and the writing of the report 

主　　题：Anabolic Androgenic Fenugreek seeds Glycosides Randomized controlled study Resistance training 

摘      要：Purpose： To evaluate the efficacy and safety of the glycoside fraction of fenugreek （Trigonellafoenum-graecum） seeds （Fenu-FG） on physiologi- cal parameters related to muscle anabolism, androgenic hormones, and body fat in healthy male subjects during an 8-week resistance training program using a prospective, randomized, double-blind, placebo controlled design. Methods： Sixty healthy male subjects were randomized to ingest capsules of Fenu-FG （1 capsule of 300 rag, twice per day） or the matching placebo at a 1：1 ratio. The subjects participated in a supervised 4-day per week resistance-training program for 8 weeks. The outcome measurements were recorded at recruitment （baseline） and at the end of the treatment （8 weeks）. The efficacy outcome included serum testosterone （total and free） levels, muscle strength and repetitions to failure, metabolic markers for anabolic activity （serum creatinine and blood urea nitrogen）, and % body fat. The standard safety measurements such as adverse events monitoring, vital signs, hematology, biochemistry, and urinalysis were performed. Results： Fenu-FG supplementation demonstrated significant anabolic and androgenic activity as compared with the placebo. Fenu-FG treated subjects showed significant improvements in body fat without a reduction in muscle strength or repetitions to failure. The Fenu-FG supplemen- tation was found to be safe and well-tolerated. Conclusion： Fenu-FG supplementation showed beneficial effects in male subjects during resistance training without any clinical side effects.