CD163 promotes hematoma absorption and improves neurological functions in patients with intracerebral hemorrhage

作     者：Wen-jing Xie Hong-quan Yu Yu Zhang Qun Liu Hong-mei Meng 

作者机构：Department of Neurology and Neuroscience CenterFirst Hospital of Jilin University Department of NeurosurgeryFirst Hospital of Jilin University 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2016年第11卷第7期

页      面：1122-1127页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：hematoma intracerebral neurological hemoglobin NIHSS metabolism macrophage slower traumatic scavenger 

摘      要：Clinical outcomes are positively associated with hematoma *** monocyte-macrophage scavenger receptor,CD163,plays an important role in the metabolism of hemoglobin,and a soluble form of CD163 is present in plasma and other tissue fluids;therefore,we speculated that serum CD163 affects hematoma absorption after intracerebral *** with intracerebral hemorrhage were divided into high-and low-level groups according to the average CD163 level（1,977.79 ± 832.91 ng/m L）.Compared with the high-level group,the low-level group had a significantly slower hematoma absorption rate,and significantly increased National Institutes of Health Stroke Scale scores and modified Rankin Scale *** results suggest that CD163 promotes hematoma absorption and the recovery of neurological function in patients with intracerebral hemorrhage.