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One-pot synthesis of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives via the three-component reaction of 1,2-diamines, ethyl pyruvate and α-bromo ketones

One-pot synthesis of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives via the three-component reaction of 1,2-diamines, ethyl pyruvate and α-bromo ketones

作     者:Mohammad Piltan 

作者机构:Department of Chemistry Sanandaj Branch Islamic Azad University 

出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期:2014年第25卷第11期

页      面:1507-1510页

核心收录:

学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基  金:Sanandaj Branch Islamic Azad UniversityResearch Council for the financial support of this research 

主  题:Pyrrolo[1 2-a]quinoxaline a-Bromo ketones 1 2-Diamines Ethyl pyruvate 

摘      要:A simple synthetic protocol has been developed involving the three-component reaction between 1,2-diamines, ethyl pyruvate and a-bromo ketones in the presence of Fe Cl3 as a catalyst. A number of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives were synthesized in excellent yields using this protocol.

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