Notification Rate of Tuberculosis among Migrants in China 2005-2014： A Systematic Review and Meta-analysis

作     者：Yi-Xuan Sun Lei Zhu Zu-Hong Lu Zhong-Wei Jia Sun Yi-Xuan;Zhu Lei;Lu Zu-Hong;Jia Zhong-Wei

作者机构：Department of Drug Epidemiology National Institute of Drug Dependence Health Science Center Peking University Beijing 100191 China Department of Epidemiology and Biostatistics School of Public Health Health Science Center Peking University Beijing 100191 China Department of Biomedical Engineering College of Engineering Peking University Beijing 100871 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2016年第129卷第15期

页      面：1856-1860页

核心收录：

学科分类：0821[工学-纺织科学与工程] 02[经济学] 0202[经济学-应用经济学] 020208[经济学-统计学] 07[理学] 08[工学] 0714[理学-统计学（可授理学、经济学学位）] 070103[理学-概率论与数理统计] 082101[工学-纺织工程] 0701[理学-数学] 

基　　金：We would like to thank Jin-Kou Zhao of the Global Fund in Geneva  and Allison Rhines for language assistance. We also thank Pei-Pei Ding of Beijing Normal University  for her help in searching literature and in spatial analysis.This work was supported by the National Nature Science Foundation (No. 61571001 91546203) 

主　　题：Meta-analysis Migrants Notification Rate Systematic Review Tuberculosis 

摘      要：Background： Migrations have been reported to be associated with the high risk of tuberculosis （TB）, but there is no systematic analysis of the available data for TB among migrant in China. The aim of this study was to examine the notification rate of active and sputum smear-positive TB by a systematic review and meta-analysis. Methods： A systematic review and meta-analysis were performed to examine the notification rate of active and sputum smear-positive TB among migrants in China. Two reviewers searched the cross-sectional studies published in PubMed, EMBASE, SciFinder, and Web of Science in English and in CNKI and Wanfang databases in Chinese. Pooled estimates of notification rate of TB among migrants were calculated using a random effects model. Meta-regression analysis and subgroup analysis stratified by year, region were also performed. Results： Seventy eligible studies met the inclusion criteria for the final analysis. The overall notification rate of active TB and sputum smear-positive cases among migrants were 53.12 （95% confidence interval [CI]： 47.32 59.63） and 24.53 （95% Cl： 22.01-27.34） per 100,000 populations, respectively. The notification rate of active TB significantly increased from 50.95 （95% CI： 41.11 -63.14） per 100,000 populations in 2005 to 84.62 （95% CI： 78.00-91.80） per 100,000 populations in 2014 while that of smear-positive TB was constant during the study time （P = 0.79）. The geographic difference was identified both for active and sputum smear-positive TB, with the higher notification rates mainly distributing along the eastern coastal areas. Conclusions： The pooled estimate of active TB and sputum smear-positive TB among migrants was lower than the national notification rate among general population, but the gap between our data and national notification rate among general population is narrowed down during 2005-2014.