Reorganization of spinal neural circuitry and functional recovery after spinal cord injury

作     者：Raffaele Nardone Eugen Trinka 

作者机构：Department of Neurology Christian Doppler Klinik Paracelsus Medical University Spinal Cord Injury and Tissue Regeneration Center Paracelsus Medical University Department of Neurology Franz Tappeiner Hospital 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2015年第10卷第2期

页      面：201-202页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：SCI Reorganization of spinal neural circuitry and functional recovery after spinal cord injury TSR 

摘      要：The ability of the adult central nervous system to reorganize its circuits over time is the key to understand the functional improvement in subjects with spinal cord injury （SCI）. Adaptive changes within spared neuronal circuits may occur at cortical, brainstem, or spinal cord level, both above and below a spinal lesion （Bareyre et al., 2004）. At each level the reorganization is a very dynamic process, and its degree is highly variable, depending on several factors, including the age of the subject when SCI has occurred and the rehabilitative therapy. The use of electrophysiological techniques to assess these functional changes in neural networks is of great interest, because invasive methodologies as employed in preclinical models can obviously not be used in clinical studies.